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REVIEW ARTICLE
Year : 2016  |  Volume : 1  |  Issue : 4  |  Page : 109-117

Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases


1 Division of Environmental Health Sciences, College of Public Health, Ohio State University, Columbus, Ohio, USA
2 Division of Environmental Health Sciences, College of Public Health; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China; Davis Heart and Lung Research Institute, College of Medicine, Ohio State University, Columbus, Ohio, USA

Correspondence Address:
Qinghua Sun
Division of Environmental Health Sciences, College of Public Health, Ohio State University, Columbus, Ohio, USA

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2468-5690.198616

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Cardiovascular diseases refer to all disorders related to the heart and its circulatory system, such as atherosclerosis, arrhythmia, hypertension, and stroke. In recent years, numerous environmental studies in humans and animal models have confirmed a positive association between ambient particulate matter (PM) exposure and cardiovascular morbidity/mortality. The deleterious impacts of the exposure are involved in multiple mechanisms, in which one is due to the pro-inflammatory effects that result from the peroxidation of lipids, which provide critical structure and function in cellular membranes, the main sites of pollutant attack. This review aims to assess the current scientific literature relating to pertinent mechanisms, molecular pathways, and at-risk populations associated with cardiovascular complications induced by ambient PM exposure.


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